Neutralizing antibody response in bovine serum and nasal and salivary secretions after immunization with live or inactivated food-and-mouth disease virus.

Neutralizing Antibody Response in Bovine Serum and Nasal and Salivary Secretions After Immunization with Live

Local immunity seems to play a major role in the resistance to infection by rhinoviruses (10). Since foot-and-mouth disease virus (FMDV) shows many of the features of a rhinovirus (8), local immunity in cattle could provide resistance against the disease (7), and it would be possible to appraise it by searching for neutralizing antibodies in nasal secretions. The present work is an investigatio...

Neutralizing Antibody Response in Bovine Serum and Nasal and Salivary Secretions After Immunization with Live

Local immunity seems to play a major role in the resistance to infection by rhinoviruses (10). Since foot-and-mouth disease virus (FMDV) shows many of the features of a rhinovirus (8), local immunity in cattle could provide resistance against the disease (7), and it would be possible to appraise it by searching for neutralizing antibodies in nasal secretions. The present work is an investigatio...

Neutralizing Antibody Response in Bovine Serum and Nasal and Salivary Secretions After Immunization with Live

Local immunity seems to play a major role in the resistance to infection by rhinoviruses (10). Since foot-and-mouth disease virus (FMDV) shows many of the features of a rhinovirus (8), local immunity in cattle could provide resistance against the disease (7), and it would be possible to appraise it by searching for neutralizing antibodies in nasal secretions. The present work is an investigatio...

Assessment of Serum Neutralizing Antibody Titers against Foot-and-Mouth Disease Virus A and O in Young Colostrum-Fed Dairy Calves

CpG-DNA enhancement the immune elicited as adjuvant of foot- and- mouth disease vaccine

In the present study the effect of the locally produced genetic adjuvant of ginea pig specific CpG-motif-containing oligodeoxynucleotide (CpG-ODN) in an inactivated FMD virus vaccine was evaluated. Boosting the ginea pigs with FMD vaccine along with CpG-ODN adjuvant produced relatively higher ratio (5-fold) of FMDV-specific IgG2a / IgG1 than those vaccinated in the absence of CpG-ODN. The neutr...